Our Research Focus
The Clinical Muscle Physiology Laboratory is dedicated to advancing the understanding of vascular biology and skeletal muscle physiology. Our mission is to develop innovative solutions for patients suffering from peripheral artery disease (PAD) and similar vascular conditions. Utilizing state-of-the-art human and animal tissue-based models, we aim to generate actionable insights that drive drug discovery and device development.
Our laboratory integrates cutting-edge image and omics analytics to produce data that is ready to inform clinical decisions. We specialize in creating organoid systems, engineering microphysiological platforms, and executing comprehensive analytical pipelines. Through collaboration with biotech and med-tech teams, we strive to push the boundaries of research and improve patient outcomes. We are also committed to fostering scientific education by creating engaging visual content to demystify complex concepts in our field.
Meet Our Team
Our team comprises dedicated researchers and experts in muscle physiology and vascular biology. Each member brings unique skills and knowledge, contributing to our laboratory's innovative research initiatives.
Dr. Panagiotis Koutakis
Biomedical Scientist
Dr. Panagiotis Koutakis is a muscle physiologist whose research program centers on the pathophysiology of cardiovascular disease. His research insterests are in ischemia and reperfusion injury, reactive oxygen species, impaired mitochondrial bioenergetics, and oxidative damage in the skeletal muscle.
Dr. Iraklis I. Pipinos
Vascular Surgeon
Dr. Pipinos is a vascular surgeon and professor in the Department of Surgery at the University of Nebraska Medical Center. His research focuses on evaluating the pathophysiology of the myopathy and neuropathy of the ischemic legs with peripheral artery disease, the functional impairment it produces in patients and the optimal ways to diagnose and treat it.
Dr. Emma Fletcher
Instructor
Emma is an independent researcher investigating the interplay between the skeletal muscle and vascular tissue.
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Evlampia Papoutsi
Research Coordinator
Eva works on developing organoid models to study the cellular mechanisms of vascular diseases. Her innovative approach enhances our research capabilities.
Paraskevi Patsalia
Research Assistant
Georgia is involved in data analysis and interpretation, leveraging her expertise in omics technologies to support our research objectives.
Joshua Mammen
Undergraduate Student
Joshua involves assisting with various experiments, ensuring accurate results, and maintaining a safe and organized workspace.
Eva Longo
Undergraduate Student
Eva assists in the laboratory's daily operations in experimental setups.